A fatal, degenerative neurological disease of sheep and goats. Belonging to a family of diseases known as transmissible spongiform encephalopathies (TSEs), scrapie is similar to bovine spongiform encephalopathy (BSE) (mad cow), a disease of cattle. There is no scientific evidence to indicate that scrapie poses a risk to human health. The Animal and Plant Health Inspection Service conducts a Scrapie Flock Certification Program to certify scrapie-free herds and a Scrapie Eradication Program to accelerate the eradication of scrapie from the United States.